Purchase a Skill

Engage in all optional conversations

Defeat Black Fang without getting hit

Collect all comics

Break into every locked door using shivs

Pet Buckley the dog

Pick up Frank's note after it's discarded

Play the Jak X game in Left Behind

Use bricks or bottles to lure an infected into attacking a human

Win the brick throwing contest

Place 9 fully explored, adjacent Maps into 9 Item Frames in a 3 by 3 square.

Use the Totem of Undying to cheat death.

All trophies have been awarded.