The player has successfully completed the Welcome To Rapture Level

The player has defeated Peach Wilkins

The player has completed Sander Cohen's great masterpiece

The player has broken Fontaine's mind control

The player has defeated Atlas

Purchased every slot in all four Plasmid and Tonic tracks

The player has acquired at least one weapon upgrade

The player has fully upgraded two weapons

Fully upgrade four weapons

Acquire all upgrades for all weapons

The player has fully researched the Leadhead Splicer

Fully research the Houdini Splicer

Fully research the Rosie

Fully research the Little Sister

Max out all possible research

The player has taken at least one Research Photo of a Splicer

The player has successfully hacked a security bot

The player has successfully hacked a turret

The player has successfully hacked a safe

The player has successfully invented at least one item

The player has successfully invented all possible ammo types

Collect or Invent 58 Tonics in the Physical, Engineering and Combat tracks

The player has completed the game on the Hard difficulty setting

Hit the jackpot at a slot machine

The player has entered Sander Cohen's personal quarters

Complete the game on Hard difficulty without using a Vita-Chamber

Complete the game on Survivor difficulty without using a Vita-chamber

Rescued the Little Sister in “The ‘I’ in Team” in under 3:00

Rescued the Little Sister in “The ‘I’ in Team” without destroying any Machine Gun Turrets

The player has rescued the Little Sister in “A Shocking Turn of Events” in under 4:00

Charged up the Ferris Wheel 9 different times in “A Shocking Turn of Events”

Rescued the Little Sister in “Worlds of Hurt” in under 15:00, on Medium or higher difficulty

Rescued the Little Sister in “Worlds of Hurt” using only plasmids, tonics, the wrench, and the research camera, on Medium or higher difficulty